MycoScan™

Turn cell‑free DNA into clarity

A 3-hour pan-fungal liquid biopsy. Detect, identify, and quantify invasive fungal pathogens directly from blood — with the speed of PCR and the breadth of sequencing.

3 hr Sample to result

>50 Species detected

1 copy Genome copy sensitivity

dPCR Standard platforms

The Clinical Challenge

Invasive fungal infections are hard to detect early

Immunocompromised patients face life-threatening invasive fungal infections with mortality rates approaching 50% despite treatment. Current diagnostics force clinicians into impossible trade-offs.

Culture is slow

Traditional methods yield results in days to weeks, with poor sensitivity for deep-seated infections.

PCR panels are narrow

Existing PCR tests are fast but cover only a handful of species, missing critical pathogens.

NGS is costly & complex

Next-generation sequencing offers breadth but requires specialized equipment, expertise, and days of turnaround.

MycoScan™

A breakthrough assay

MycoScan is a unique, powerful assay that detects microbial cell-free DNA in plasma. It combines speed, breadth, and accessibility in a single test.

3-hour turnaround

Sample-to-result in hours, not days, enabling timely clinical decisions.

Broad coverage

Dozens of clinically relevant molds, yeasts, and dimorphic fungi. Species-level where it matters.

Standard dPCR platforms

No specialized sequencing equipment required. Runs on general-purpose hardware already in labs.

Cost-efficient

Simpler and more affordable than NGS while maintaining comprehensive coverage.

Envisioned Benefits

Built for every stakeholder

For Patients

Detect infections early and track progression over treatment for better outcomes.

For Providers

Reduce testing costs and align molecular results with evolving clinical guidelines.

For Labs

Operate an efficient test on general-purpose dPCR hardware you may already have.

Proprietary Technology

Powered by SKIP‑SEQ™

Smart Keywords of Informative Primer Sequences

With underlying technology from Rice University, we design compact sets of informative probe-primer "keywords" to profile targeted cfDNA fragments. Each pathogen has a signature combination of keywords across many fragments, and dPCR allows fragments to be measured one molecule at a time.

Our reconstruction algorithm solves for the abundance of the pathogens — multiplexing the information, not the cost. No sequencing required.

Download Whitepaper

Sample

Cell-free DNA extracted from patient plasma

Amplify

Informative probe-primer keywords on dPCR

Decode

Algorithmic fingerprints identify species & abundance

Report

Actionable results in under 3 hours

Organism Coverage

Panel in development

Our panel focuses on organisms associated with infections where culture-based tests have especially low yield. We are continuously seeking feedback on panel composition — let us know what matters most to your practice.

Molds

Alternaria spp.
Aspergillus calidoustus
Aspergillus flavus
Aspergillus fumigatus
Aspergillus lentulus
Aspergillus nidulans
Aspergillus niger
Aspergillus terreus
Aspergillus spp.
Exophiala spp.
Fusarium oxysporum
Fusarium solani
Fusarium spp.
Lomentospora prolificans
Mucorales
Scedosporium apiospermum

Yeasts

Candida spp.
Cryptococcus gattii
Cryptococcus neoformans
Pneumocystis jirovecii
Trichosporon spp.

Dimorphic

Blastomyces dermatitidis
Coccidioides immitis
Coccidioides posadasii
Histoplasma capsulatum
Paracoccidioides brasiliensis
Paracoccidioides lutzii
Sporothrix schenckii
Talaromyces marneffei

Fungal mimickers

Legionella spp.
Nocardia spp.

Interested in collaboration?

We have begun on-site research evaluations of a beta version of our kit at leading institutions. We are always seeking passionate collaborators for clinical research and feedback on our assay specifications.